Pyrimidines And Derivatives

Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.

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3,706 – 3,720 of 7,454 results

3,706

Medchemexpress LLC Dapaconazole | 1269726-67-1 | 99.8% | 415.24 | 50 MG

Dapaconazole is an antifungal agent known for its ability to inhibit sterol 14α-demethylase cytochrome P450 activity. This compound has demonstrated efficacy in inhibiting key fungal enzymes and has been investigated in clinical trials for conditions such as Tinea Cruris and Tinea Pedis. It is characterized by high purity and specific chemical properties.

Inhibits sterol 14α-demethylase cytochrome P450 activity
Investigated in clinical trials for antifungal applications
High purity
Solid appearance

Pricing & Availability

3,707

eMolecules 1394854-52-4 | Medchem Express | GSK-J2 | 10mg | 446266239 | HY-15648A | MFCD27991274 | 389.459 | C22H23N5O2

Ambeed | tert-Butyl 1-bromo-2-oxo-691215-tetraoxa-3-azaoctadecan-18-oate | 250mg | 649270162 | A677171 | 1807521-00-1 | MFCD28505519 | 442.347 | C17H32BrNO7

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3,708

Medchemexpress LLC Dimboa | 15893-52-4 | 10 MG

DIMBOA, a benzoxazinoid, serves as a chemical defense in graminaceous plants like maize, wheat, and rye. It inhibits the growth of bacteria such as *Staphylococcus aureus* and *Escherichia coli*, and fungi including *Saccharomyces cerevisiae*. Demonstrating antioxidant activity, DIMBOA shows potent free-radical scavenging and inhibits the biosynthesis of toxic trichothecenes, thereby reducing plant susceptibility to scab. It also exhibits cytotoxicity to plant cells.

Functions as a chemical defense in graminaceous plants
Inhibits growth of bacteria and fungi
Potent free-radical scavenging and antioxidant properties
Inhibits biosynthesis of toxic trichothecenes
Reduces plant susceptibility to scab
Exhibits cytotoxicity to plant cells
For research use only

Pricing & Availability

3,709

eMolecules 630116-52-8 | AstaTech | 4-O-TOLYLPIPERIDINE | 0.25g | 268503647 | BL008747 | 95 | MFCD05189913 | 175.275 | C12H17N

AstaTech | 4-O-TOLYLPIPERIDINE | 0.25g | 268503647 | BL008747 | 95.000 | 630116-52-8 | MFCD05189913 | 175.275 | C12H17N

Pricing & Availability

3,710

Medchemexpress LLC 2,3,4,5-Tetracaffeoyl-D-Glucaric acid | 1419478-52-6 | 5 MG

2,3,4,5-Tetracaffeoyl-D-Glucaric acid is a caffeoyl-D-glucaric acid derivative isolated from the Genus Gnaphalium, intended for research use only.

Isolated from the genus Gnaphalium
Purity of 99.29%
Molecular weight of 858.71
Formula: C42H34O20
Appears as an off-white to light yellow solid
Initial source includes various plants
Classified as phenylpropanoid
Soluble in DMSO at 100 mg/mL
Used in inflammation/immunology research

Pricing & Availability

3,711

Medchemexpress LLC 5S rRNA modificator (FAI) | 1415238-77-5 | 95.61% | 176.17 | 1 MG

5S rRNA modificator is an electrophile suitable for 2'-hydroxyl acylation on structured RNA molecules. It yields accurate structural information comparable to that obtained with existing probes, and is used in 5S rRNA RNA modification research. For research use only.

Suitable for 2'-hydroxyl acylation on structured RNA molecules
Provides accurate structural information
Used in RNA modification research

Pricing & Availability

3,712

Medchemexpress LLC Bevenopran | 676500-67-7 | MFCD26967979 | 99.8% | 386.44 g/mol | C20H26N4O4 | 50 MG

Bevenopran is a peripherally acting μ-opioid receptor antagonist, with additional activity at δ-opioid receptors, investigated for treatment of opioid-induced bowel dysfunction. It is supplied as a high-purity research compound for use in in vitro and in vivo pharmacology studies.

Peripherally acting μ-opioid receptor antagonist with δ-opioid receptor activity.
Intended for research use in studies of opioid-induced bowel dysfunction and related pharmacology.
High purity (99.82%) suitable for in vitro and in vivo experiments.
Molecular weight 386.44 g/mol; chemical formula C20H26N4O4.
CAS number 676500-67-7 for unambiguous substance identification.
Available as solid quantities (5 mg-200 mg) and as 10 mM solution in DMSO.

Pricing & Availability

3,713

Medchemexpress LLC Dapaconazole | 1269726-67-1 | 99.8% | 415.2 g/mol | C19H15Cl2F3N2O | 10 MG

Dapaconazole is an antifungal research compound that inhibits sterol 14α-demethylase (a cytochrome P450 enzyme). It is supplied as a solid and as a DMSO solution for in vitro studies of fungal CYP51 inhibition and antifungal activity. CAS RN 1269726-67-1; molecular formula C19H15Cl2F3N2O.

Inhibits sterol 14α-demethylase with an IC50 of 1.4 μM.
High purity (99.76%) suitable for biochemical assays.
Available in small solid quantities (5-100 mg) and as a 10 mM solution in DMSO for screening.
Commonly used in in vitro antifungal and CYP51 inhibition studies.

Pricing & Availability

3,714

Medchemexpress LLC 5H-dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-ethyl-1-piperazinyl)-1-fluoro- | 2369979-67-7 | MFCD34167518 | 99.5% | C19H20ClFN4 | 10MG

JHU37152 is a potent, brain-penetrant DREADD agonist selective for hM3Dq and hM4Di receptors. In HEK-293 assays it exhibits EC50s of 5 nM (hM3Dq) and 0.5 nM (hM4Di), displaces [3H]clozapine, and is supplied as a high-purity research reagent.

High purity: 99.45%.
Cas number: 2369979-67-7.
Chemical formula: C19H20ClFN4.
Molecular weight: 358.84 g·mol⁻1.
Physical state: solid, white to yellow.
Solubility: soluble in DMSO (~33.33 mg/mL).
Storage: powder -20°C for long term; in solvent -80°C recommended.
Applications: in vitro and in vivo neuroscience research.

Pricing & Availability

3,715

Medchemexpress LLC Dapaconazole | 1269726-67-1 | 99.8% | 415.24 | 5 MG

Dapaconazole is an antifungal agent primarily known for inhibiting sterol 14α-demethylase cytochrome P450 activity. It has shown significant bioavailability in in vivo studies.

Antifungal activity
Inhibits sterol 14α-demethylase cytochrome P450 activity
IC50 of 1.4 μM against CYP26
Demonstrates 97.3% bioavailability in male beagle dogs

Pricing & Availability

3,716

Medchemexpress LLC 2-(3,5-dimethylpyrazol-1-yl)-5-methylphenol | 1391758-52-3 | 100.0% | 202.25 g/mol | C12H14N2O | 25 MG

ME1111 is a small-molecule antifungal research compound that inhibits succinate dehydrogenase in Trichophyton species and is used in onychomycosis studies due to its ability to penetrate human nails. The compound is a phenolic pyrazole derivative with formula C12H14N2O and CAS 1391758-52-3.

Inhibits fungal succinate dehydrogenase.
Active against dermatophytes.
Demonstrates good human nail penetration for onychomycosis research.
Small-molecule phenolic pyrazole with formula C12H14N2O.
High purity suitable for in vitro and in vivo research applications.

Pricing & Availability

3,717

STA PHARMACEUTICAL US LLC 2’-OTBS Pyrimidinone amidite | 200 mg | CAS 155831-90-6 | MDL MFCD08062082

2’-OTBS Pyrimidinone amidite is a Amidite reagent (Subcategory: Specialty Base Modification) sold by WuXi TIDES. Offered in 200 mg. Store at -20 °C. SDS available for reference.

Specifications
- CAS: 155831-90-6
- MDL: MFCD08062082
- InChIKey: UEUDLVPTCOPGMZ-MGVQLQBBSA-N
- Molecular Weight: 845.061761998
- Molecular Formula: C45H61N4O8PSi
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 200 mg
- Net Weight: 0.2 g
- Gross Weight: 6.9 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@@H]1[C@H](O[C@H]([C@@H]1O[Si](C)(C(C)(C)C)C)N2C(N=CC=C2)=O)COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OCCC#N)C(C)C)C

Pricing & Availability

3,718

eMolecules 873-83-6 | 6-Aminouracil | Ambeed | MFCD00068470 | 127.103 | C4H5N3O2 | 98.000 | Nc1cc(=O)[nH]c(=O)[nH]1 | 25g | 552676079

6-Aminouracil | Ambeed | 873-83-6 | MFCD00068470 | 127.103 | C4H5N3O2 | 98.000 | Nc1cc(=O)[nH]c(=O)[nH]1 | 25g | 552676079

Pricing & Availability

3,719

eMolecules 115652-52-3 | (1-Aminocyclopropyl)methanol hydrochloride | Ambeed | MFCD09834330 | 123.580 | C4H10ClNO | 97.000 | Cl.NC1(CO)CC1 | 250mg | 521396747

(1-Aminocyclopropyl)methanol hydrochloride | Ambeed | 115652-52-3 | MFCD09834330 | 123.580 | C4H10ClNO | 97.000 | Cl.NC1(CO)CC1 | 250mg | 521396747

Pricing & Availability

3,720

Medchemexpress LLC ArnicolideC | 34532-67-7 | 5 MG

ArnicolideC is a sesquiterpene lactone isolated from *Centipeda minima*. It demonstrates a cytotoxic effect on nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time-dependent manner and exhibiting inhibitory effects on NPC proliferation.

Molecular weight: 334.41
Formula: C₁₉H₂₆O₅
Appearance: Solid, white to off-white
Structure classification: Terpenoids, sesquiterpenes
Purity: 99.81%
Isolated from *Centipeda minima*
Cytotoxic effect on nasopharyngeal carcinoma (NPC) cells
Inhibits cell growth in a dose- and time-dependent manner
Inhibits NPC proliferation

Pricing & Availability

Pyrimidines And Derivatives

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Medchemexpress LLC Dapaconazole | 1269726-67-1 | 99.8% | 415.24 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dimboa | 15893-52-4 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2,3,4,5-Tetracaffeoyl-D-Glucaric acid | 1419478-52-6 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5S rRNA modificator (FAI) | 1415238-77-5 | 95.61% | 176.17 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bevenopran | 676500-67-7 | MFCD26967979 | 99.8% | 386.44 g/mol | C20H26N4O4 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dapaconazole | 1269726-67-1 | 99.8% | 415.2 g/mol | C19H15Cl2F3N2O | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5H-dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-ethyl-1-piperazinyl)-1-fluoro- | 2369979-67-7 | MFCD34167518 | 99.5% | C19H20ClFN4 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dapaconazole | 1269726-67-1 | 99.8% | 415.24 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-(3,5-dimethylpyrazol-1-yl)-5-methylphenol | 1391758-52-3 | 100.0% | 202.25 g/mol | C12H14N2O | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC ArnicolideC | 34532-67-7 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More